Anne Kolsky 1 posts Re: Topic 8 DQ 2 Clinical Significance and Statistical Significance Clinical significance can help to validate whether a treatment effect has practical importance and if it has a real effect on daily life. If a treatment makes a noticeable difference and improvement to a patient, then this is considered clinically important and significant. Statistical significance is measured through confidence intervals and p-values that quantify the significance of a treatment or trial’s effect on a patient or sample. For instance, if the p value is less than 0.05, then it tells us the trial is statistically significant. This means the result did not happen by chance. However, it does not tell us the importance or meaningfulness of the findings, only that there is something “real” happening (Leyva De Los Rios, 2017). How Clinical Significance Can Support Positive Outcomes in Capstone Project Clinical Significance can greatly support the project in many ways. For the PICOT, if scores that are compared indicate kindergarten readiness by virtue of screening over not screening, then statistical significance is established. If a body of students show marked improvements in grades, attendance, attitude, graduation rates, and staying clean, sober, and out of criminal trouble, it will lead to huge bragging rights for many stakeholders as evidenced by statistical significance in longitudinal studies that would also be established (Page, 2014). Leyva De Los Rios, C. (2017, March 23). Retrieved from https://www.students4bestevidence.net/statistical-significance-vs-clinical-significance/ Page P. (2014). Beyond statistical significance: clinical interpretation of rehabilitation research literature. International journal of sports physical therapy, 9(5), 726–736.Retreived from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197528
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